{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235197"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Gene expession profile at single cell level of renal cells from whole mouse kidneys.","description":"ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. Pkd1 deletion induced cyst growth in mouse kidneys, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole Pkd1 mutant polycystic mouse kidneys at single-cell resolution. We also generated Pkd1fl/fl:Pkhd1-Cre mice with transgenic αKlotho (Pkd1 HOMO-KLTg) to evaluate cyst growth and performed single cell RNA sequencing analysis.","dates":{"publication":"2026/05/15"},"accession":"GSE235197","cross_references":{"GSM":["GSM7496674","GSM7496675","GSM7496676","GSM7496677","GSM7496678","GSM7496679","GSM7496671","GSM7496672","GSM7496673"],"GPL":["21103"],"GSE":["235197"],"taxon":["Mus musculus"],"PMID":["[41563399]"]}}