GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235197/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235197GEOGSEfalseGene expession profile at single cell level of renal cells from whole mouse kidneys.ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. Pkd1 deletion induced cyst growth in mouse kidneys, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole Pkd1 mutant polycystic mouse kidneys at single-cell resolution. We also generated Pkd1fl/fl:Pkhd1-Cre mice with transgenic αKlotho (Pkd1 HOMO-KLTg) to evaluate cyst growth and performed single cell RNA sequencing analysis.2026/05/15GSE235197GSM7496674GSM7496675GSM7496676GSM7496677GSM7496678GSM7496679GSM7496671GSM7496672GSM749667321103235197Mus musculus[41563399]