{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235285/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235285"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Rebalancing the brain: The therapeutic potential of false neurotransmitters in excitatory-inhibitory imbalance","description":"Excitatory-inhibitory (E-I) balance results from a complex interplay between glutamatergic and GABAergic neurons, and E-I imbalance has been proposed to contribute to many neurological diseases. We have created the first excitatory (S-2-methyglutamate or S-2MeGlu) and inhibitory (R-4-aminopentanoate or R-4APA) false neurotransmitters, and using single nucleus RNA sequencing, we have tested their transcriptomic impact in wild-type mice following chronic exposure to the lowest dose","dates":{"publication":"2026/04/01"},"accession":"GSE235285","cross_references":{"GSM":["GSM7498336","GSM7498335","GSM7498329","GSM7498330","GSM7498332","GSM7498331","GSM7498334","GSM7498333"],"GPL":["24247"],"GSE":["235285"],"taxon":["Mus musculus"]}}