GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235285/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235285GEOGSEfalseRebalancing the brain: The therapeutic potential of false neurotransmitters in excitatory-inhibitory imbalanceExcitatory-inhibitory (E-I) balance results from a complex interplay between glutamatergic and GABAergic neurons, and E-I imbalance has been proposed to contribute to many neurological diseases. We have created the first excitatory (S-2-methyglutamate or S-2MeGlu) and inhibitory (R-4-aminopentanoate or R-4APA) false neurotransmitters, and using single nucleus RNA sequencing, we have tested their transcriptomic impact in wild-type mice following chronic exposure to the lowest dose2026/04/01GSE235285GSM7498336GSM7498335GSM7498329GSM7498330GSM7498332GSM7498331GSM7498334GSM749833324247235285Mus musculus