GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235686/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235686GEOGSEfalseAcute Myeloid Leukemia patient/ CD34+ healthy donor RNA-seqAML is an aggressive and heterogenous hematologic malignancy. Here, we performed bulk RNA sequencing of 16 AML patients and primary hematopoietic cell populations, CD34+ HSC and CD14+monocytes to understand transcriptional and post-transcriptional mechanisms that drive leukemogenesis and block AML differentiation. Our findings provide a better understanding of gene regulatory pathways in AML in comparison to normal hematopoietic cells, which may provide new therapeutic strategy to selectively target AML cells.2026/06/01GSE235686GSM7507895GSM7507896GSM7507893GSM7507894GSM7507891GSM7507892GSM7507890GSM7507903GSM7507904GSM7507901GSM7507902GSM7507899GSM7507888GSM7507900GSM7507889GSM7507897GSM750789824676235686Homo sapiens