GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235890/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235890GEOGSEfalseRole of mitochondrial RNase P complex in the processing of primary RNA in human mitochondriaThe human mitochondrial genome is transcribed into long polycistronic RNA that undergoes subsequent endonucleolytic processing. The role of the mitochondrial RNase P, a protein complex composed of RNA methyltransferase, ribonuclease and dehydrogenase, has been revealed in the processing of the primary mitochondrial RNA. Still, the contribution of catalytic activities of RNase P subunits in the processing of individual processing sites has not been fully described. This study aims to define the role of RNase P subunits in regulating the efficiency of the processing of the primary mitochondrial RNA.2026/06/27GSE235890GSM7511537GSM751153824676235890Homo sapiens