{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235895/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":[" Other","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235895"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Multi-tissue single-cell atlas of murine atherosclerosis","description":"Atherosclerosis is a chronic inflammatory disease in which both the innate and adaptive immune systems play a role. Our objective was to create a multi-tissue single-cell atlas of atherosclerosis using the hypercholesterolaemic Ldlr-/- Apob100/100 mouse model. We used mice fed with either a chow diet or a 3-month high fat diet to respectively represent an early state and a late state of the disease. We collected four tissues: epididymal white adipose tissue, perivascular adipose tissue, aorta, and spleen, and dissociated them into suspensions containing either all cells or enriched for CD45+ cells (aorta samples). The data has been created using 10X Genomics 5’ single-cell immuneprofiling technology.","dates":{"publication":"2026/09/17"},"accession":"GSE235895","cross_references":{"GSM":["GSM7511647","GSM7511625","GSM7511648","GSM7511626","GSM7511645","GSM7511623","GSM7511646","GSM7511624","GSM7511629","GSM7511627","GSM7511649","GSM7511628","GSM7511661","GSM7511662","GSM7511640","GSM7511660","GSM7511643","GSM7511621","GSM7511622","GSM7511644","GSM7511641","GSM7511642","GSM7511620","GSM7511636","GSM7511658","GSM7511659","GSM7511637","GSM7511656","GSM7511634","GSM7511657","GSM7511635","GSM7511618","GSM7511619","GSM7511638","GSM7511639","GSM7511617","GSM7511650","GSM7511651","GSM7511654","GSM7511632","GSM7511633","GSM7511655","GSM7511630","GSM7511652","GSM7511653","GSM7511631"],"GPL":["24247"],"GSE":["235895"],"taxon":["Mus musculus"]}}