GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235895/primaryOK200TranscriptomicsMus musculus OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235895GEOGSEfalseMulti-tissue single-cell atlas of murine atherosclerosisAtherosclerosis is a chronic inflammatory disease in which both the innate and adaptive immune systems play a role. Our objective was to create a multi-tissue single-cell atlas of atherosclerosis using the hypercholesterolaemic Ldlr-/- Apob100/100 mouse model. We used mice fed with either a chow diet or a 3-month high fat diet to respectively represent an early state and a late state of the disease. We collected four tissues: epididymal white adipose tissue, perivascular adipose tissue, aorta, and spleen, and dissociated them into suspensions containing either all cells or enriched for CD45+ cells (aorta samples). The data has been created using 10X Genomics 5’ single-cell immuneprofiling technology.2026/09/17GSE235895GSM7511647GSM7511625GSM7511648GSM7511626GSM7511645GSM7511623GSM7511646GSM7511624GSM7511629GSM7511627GSM7511649GSM7511628GSM7511661GSM7511662GSM7511640GSM7511660GSM7511643GSM7511621GSM7511622GSM7511644GSM7511641GSM7511642GSM7511620GSM7511636GSM7511658GSM7511659GSM7511637GSM7511656GSM7511634GSM7511657GSM7511635GSM7511618GSM7511619GSM7511638GSM7511639GSM7511617GSM7511650GSM7511651GSM7511654GSM7511632GSM7511633GSM7511655GSM7511630GSM7511652GSM7511653GSM751163124247235895Mus musculus