GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE23nnn/GSE23635/primaryOK2000000GenomicsMus musculusExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23635GEOGSE0falseConversion of mouse fibroblast to hepatocyte-like cells by defined factorsPlasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (Hnf1alpha, Gata4, and Foxa3) and p19Arf inactivation, tail-tip fibroblasts can be converted to hepatocyte-like (iHep) cells, expressing hepatocyte marker genes, and acquiring many mature hepatocyte functions in vitro and in vivo.2011/05/11GSE23635GSM703110GSM703103GSM703114GSM703113GSM703112GSM703111GSM703107GSM703106GSM703105GSM703104GSM703115GSM703109GSM703108413423635Mus musculus[21562492]