{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Csv":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/suppl/GSE240703_all_samples_count.csv.gz","ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/suppl/GSE240703_all_samples_fpkm.csv.gz"],"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240703"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"The effect of Sphingosine-1-Phosphate Receptor 1 and Complement Component 3 conditional knockouts on primary tumors in MMTV-PyMT mice.","description":"Sphingolipid metabolism has been shown to regulate intracellular complement activation via sphingosine-1-phosphate receptor 1 (S1PR1) signaling to stimulate NLRP3 inflammasome-induced cancer metastasis. Here, the transcriptomic effects of S1PR1 and complement C3 conditional knockouts on primary tumors in MMTV-PyMT Mice were assessed.","dates":{"publication":"2026/08/11"},"accession":"GSE240703","cross_references":{"GSM":["GSM7707650","GSM7707640","GSM7707641","GSM7707642","GSM7707643","GSM7707644","GSM7707645","GSM7707646","GSM7707647","GSM7707648","GSM7707649","GSM7707639"],"GPL":["24247"],"GSE":["240703"],"taxon":["Mus musculus"]}}