GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/suppl/GSE240703_all_samples_count.csv.gzftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/suppl/GSE240703_all_samples_fpkm.csv.gzftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240703/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240703GEOGSEfalseThe effect of Sphingosine-1-Phosphate Receptor 1 and Complement Component 3 conditional knockouts on primary tumors in MMTV-PyMT mice.Sphingolipid metabolism has been shown to regulate intracellular complement activation via sphingosine-1-phosphate receptor 1 (S1PR1) signaling to stimulate NLRP3 inflammasome-induced cancer metastasis. Here, the transcriptomic effects of S1PR1 and complement C3 conditional knockouts on primary tumors in MMTV-PyMT Mice were assessed.2026/08/11GSE240703GSM7707650GSM7707640GSM7707641GSM7707642GSM7707643GSM7707644GSM7707645GSM7707646GSM7707647GSM7707648GSM7707649GSM770763924247240703Mus musculus