GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE245nnn/GSE245618/suppl/GSE245618_rel-table-7_all_90_samples_.xlsxftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE245nnn/GSE245618/suppl/GSE245618_abs-abund-table-7_all_90_samples_.xlsxftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE245nnn/GSE245618/primaryOK200OtherMus musculusOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE245618GEOGSEfalseFecal and epithelial microbiota in Apc(Min/+) and wild-type littermatesAccumulating evidence suggests a strong link between intestinal microbiota and colorectal cancer initiation, beyond genetic factors. The origins of dysbiosis (altered microbiota composition) remain poorly understood, especially in genetically susceptible hosts. Our previous study has demonstrated that the presence of intraepithelial bacteria as a consequence of intestinal barrier dysfunction shaped dysbiotic microbiota that contributed to colitis development. Here, we evaluated the fecal and epithelial microbiota in age-matched Apc(Min/+) and wild-type littermates. The fecal samples and purified epithelial cells from intestinal segments (ileum and colon) were collected at various time points for analysis of microbiota composition by PacBio full-length 16S rRNA gene sequencing.2026/07/08GSE245618GSM7845880GSM7845881GSM7845882GSM7845843GSM7845800GSM7845844GSM7845845GSM7845801GSM7845802GSM7845846GSM7845883GSM7845840GSM7845884GSM7845885GSM7845841GSM7845842GSM7845807GSM7845808GSM7845809GSM7845803GSM7845847GSM7845848GSM7845804GSM7845805GSM7845849GSM7845806GSM7845854GSM7845810GSM7845811GSM7845855GSM7845812GSM7845856GSM7845857GSM7845813GSM7845850GSM7845851GSM7845852GSM7845853GSM7845818GSM7845819GSM7845814GSM7845858GSM7845859GSM7845815GSM7845816GSM7845817GSM7845860GSM7845865GSM7845821GSM7845822GSM7845866GSM7845823GSM7845867GSM7845868GSM7845824GSM7845861GSM7845862GSM7845863GSM7845820GSM7845864GSM7845829GSM7845825GSM7845869GSM7845826GSM7845827GSM7845828GSM7845870GSM7845871GSM7845799GSM7845832GSM7845876GSM7845877GSM7845833GSM7845834GSM7845878GSM7845879GSM7845835GSM7845872GSM7845796GSM7845873GSM7845797GSM7845874GSM7845830GSM7845831GSM7845798GSM7845875GSM7845836GSM7845837GSM7845838GSM784583929177245618Mus musculus[42376755]