{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE249nnn/GSE249551/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Mus musculus"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE249551"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell muti-omics delineates the dynamics of distinct epigenetic codes coordinating mouse gastrulation","description":"Our study used CoBATCH to profile the H3K27ac and H3K4me1 states in mouse embryos at six continuous developmental stages ranging from Pre-Primitive Streak to Early Headfold stages, we comprehensively analyzed two histone markers and integrative scRNA-seq query dataset. Finally, we constructed a gene regulatory network centered on pivotal transcription factors and unraveled the mechanisms of how enhancers usage coordinates the transition of gene expression along lineage progression.","dates":{"publication":"2024/10/01"},"accession":"GSE249551","cross_references":{"GSM":["GSM7949971","GSM7949970","GSM7949964","GSM7949963","GSM7949974","GSM7949973","GSM7949972","GSM7949968","GSM7949967","GSM7949966","GSM7949965","GSM7949969"],"GPL":["24247"],"GSE":["249551"],"taxon":["Mus musculus"],"PMID":["[40340740]"]}}