{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE253nnn/GSE253841/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Homo sapiens"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE253841"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Massively Parallel Reporter Assay for 3'-UTR Variants Associated with Neurological Disorders in brain tissue cell lines","description":"Although genome-wide association studies (GWAS) have identified loci associated with alcohol consumption and alcohol use disorder (AUD), they do not identify which variants are functional. To approach this, we evaluated the impact of variants in 3’ untranslated regions (3’-UTRs) of genes in loci associated with substance use and neurological disorders using a massively parallel reporter assay (MPRA) in neuroblastoma and microglia cells.","dates":{"publication":"2026/06/15"},"accession":"GSE253841","cross_references":{"GSM":["GSM8028547","GSM8028536","GSM8028558","GSM8028557","GSM8028546","GSM8028535","GSM8028549","GSM8028538","GSM8028537","GSM8028548","GSM8028539","GSM8028550","GSM8028541","GSM8028552","GSM8028540","GSM8028551","GSM8028543","GSM8028554","GSM8028542","GSM8028553","GSM8028545","GSM8028556","GSM8028555","GSM8028544"],"GPL":["24676"],"GSE":["253841"],"taxon":["Homo sapiens"]}}