GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE267nnn/GSE267409/primaryOK200Methylation profilingHomo sapiensMethylation profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267409GEOGSEfalseTET2 affects keratinocytes and psoriatic dermatitis by regulating MECOM and NTRK1 hydroxymethylationThe ten-eleven translocation (TET) family dioxygenases TET2 oxidize 5-methylcytosine (5-mC) to 5-hmC in DNA. DNA hydroxymethylation is the most crucial epigenetic modifications in the occurrence and development of a variety of skin diseases. The goal is to determine the targets of TET2 knockdown including DNA hydroxymethylation in keratinocytes. We profiled a number of important signaling pathways and key factors that may be associated with psoriasis hydroxymethylation and may be potential biomarkers for psoriasis.2026/06/01GSE267409GSM8265313GSM8265312GSM8265315GSM826531413497267409Homo sapiens