{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE270nnn/GSE270548/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Pseudomonas aeruginosa"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE270548"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Perception of a quorum sensing signal by cell surface immune receptors increases plant disease resistance","description":"Bacterial quorum sensing (QS) during pathogenesis is an indicator of increasing danger. How sessile plants perceive QS for defense is unclear. Here, we show that Arabidopsis thaliana perceives 2'-aminoacetophenone (2’-AA), a volatile QS signal from Pseudomonas aeruginosa, through cell surface pattern recognition receptor (PRR) complexes, resulting in multistrategic defense and disease resistance. The 2’-AA-induced plant immunity requires chemical and genetic specificity. 2’-AA binds to the cytoplasmic domain of BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) and induces the formation of PRR complexes that initiate the plant immune responses. 2’-AA stimulates plant exudation of acetic acid, a volatile compound that effectively quenches QS and inhibits P. aeruginosa virulence. Plants exposed to 2’-AA reshaped the root microbiome by suppressing the abundant Pseudomonad taxa with increased bacterial diversity. These results illustrate the ability of plants to perceive and respond to pathogen QS.","dates":{"publication":"2026/04/16"},"accession":"GSE270548","cross_references":{"GSM":["GSM8346509","GSM8346510","GSM8346508","GSM8346507","GSM8346506","GSM8346505"],"GPL":["18287"],"GSE":["270548"],"taxon":["Pseudomonas aeruginosa"]}}