{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE271nnn/GSE271516/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE271516"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in Diffuse large B-cell lymphoma","description":"Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, characterized by high aggressiveness and rapid growth.Erianin, a natural compound derived from the Chinese herb Dendrobium, has been proven to have anti-cancer effects in some types of cancer, but its role and mechanism in DLBCL have not yet been reported. Therefore, this study aims to investigate whether Erianin can be a potential therapeutic drug for DLBCL.RNAseq was performed on SU-DHL-8 cells after treating with 100nM Erianin or DMSO for 24 h.","dates":{"publication":"2026/07/01"},"accession":"GSE271516","cross_references":{"GSM":["GSM8378209","GSM8378208","GSM8378212","GSM8378213","GSM8378210","GSM8378211"],"GPL":["23227"],"GSE":["271516"],"taxon":["Homo sapiens"]}}