{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE274nnn/GSE274047/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE274047"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Study of gene expression in mouse primary hepatocytes cultured in hydrogels with different stiffnesses in wild-type and YAP/TAZ knockout.","description":"Liver stiffness is extensively utilized as a crucial indicator in the diagnosis and monitoring of MASLD, the contribution of increased stiffness on impaired liver functions and its molecular mechanisms remains poorly understood. Wild-type or Yap/Taz knock-out hepatocytes were cultured on soft (1 kPa) and stiff (20 kPa) hydrogels to embody healthy and fibrotic livers and subjected to metabolomic and transcriptomic analyses.","dates":{"publication":"2026/05/15"},"accession":"GSE274047","cross_references":{"GSM":["GSM8442472","GSM8442470","GSM8442471","GSM8442469","GSM8442467","GSM8442468","GSM8442465","GSM8442466"],"GPL":["24247"],"GSE":["274047"],"taxon":["Mus musculus"],"PMID":["[41747066]"]}}