GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE276nnn/GSE276006/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE276006GEOGSEfalseCD40ag Activated B Cells Elicit Anti-Tumor Immunity [scRNAseq]We leveraged mouse models of Triple Negative Breast cancer of varying tumor mutation burdens to elucidate ways that direct activation of B cells can illiciate an anti-tumor effect. These syngenic tranplant models were treated with a combination of CD40 agonist immunotherapy or anti-CD19. Primary tumors of both treated and nontreated conditions were profiled by RNA-SEQ. These tumors that have been profiled describe the impact that B cell acitvation has on CD40 agonist immunotherapy treatment and tumor progression.2026/08/13GSE276006GSM8489315GSM84893142110330172276006Mus musculus