GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE276nnn/GSE276342/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE276342GEOGSEfalseHyperploidy is the intermediate state of hepatocyte transforming into ICCPolyploid cells frequently appear in tumor tissues, but it is not yet conclusively determined whether polyploid cells promote or inhibit tumor development. In this study, we combine two characteristics of hepatocytes—polyploidy and high plasticity—to investigate the role of polyploidy in the transdifferentiation of hepatocytes into precursor cells, as well as its role and mechanism in the further development of intrahepatic cholangiocarcinoma.2026/05/20GSE276342GSM8496778GSM8496779GSM8496776GSM8496777GSM8969828GSM8969827GSM8496775GSM8969829GSM8969835GSM8969834GSM8969826GSM8496780GSM8969831GSM8969830GSM8969833GSM896983224676276342Homo sapiens[40489743]