{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE278nnn/GSE278070/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":[" Genome binding/occupancy profiling by high throughput sequencing","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE278070"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Interrogating the role of a loss-of-function SETD5 mutation in hiPSC-derived astrocytes [Astrocytes_Unmerged]","description":"Intellectual disability (ID) and autism spectrum disorder (ASD) represent a spectrum of neurodevelopmental conditions with etiology often associated with genetic variations in genes encoding chromatin regulators, such as SET-domain-containing protein 5 (SETD5). Here we explore the effects of a loss-of-function SETD5 variant found in a patient with ID/ASD in human induced pluripotent stem cell (hiPSC)-derived astrocytes.","dates":{"publication":"2026/09/25"},"accession":"GSE278070","cross_references":{"GSM":["GSM8539220","GSM8539210","GSM8539221","GSM8539211","GSM8539222","GSM8539223","GSM8539212","GSM8539213","GSM8539224","GSM8539214","GSM8539215","GSM8539205","GSM8539216","GSM8539217","GSM8539206","GSM8539218","GSM8539207","GSM8539208","GSM8539219","GSM8539209"],"GPL":["21697","24676"],"GSE":["278070"],"taxon":["Homo sapiens"]}}