{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE278nnn/GSE278126/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE278126"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"scRNAseq of brain micrometastasis","description":"Heterogeneity of brain micrometastasis was analyzed by terms of intracardiac injection of H2030-BrM cell (lung adenocarcinoma model with tropism to the brain) into mice. After 14 days, mice were sacrified in order to obtain metastatic cells from micrometastases performing vascular co-option and in proliferative pause to study their heterogeneity. Apart from control cells, H2030-BrM with reduced levels of MXD4 (shRNAs), a discovered driver of the prolfierative pause, were also injected and analyzed by scRNAseq to compare their differences.","dates":{"publication":"2026/08/21"},"accession":"GSE278126","cross_references":{"GSM":["GSM8540543","GSM8540544"],"GPL":["34281"],"GSE":["278126"],"taxon":["Homo sapiens"]}}