GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE280nnn/GSE280827/primaryOK200GenomicsMus musculusGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280827GEOGSEfalseChIP-seq of H3K27ac and H3K27me3 in the hippocampus of C57BL/6 mice after high methionine feeding for more than 8 weeks.To explore whether high homocysteine status affects the enrichment of histone H3K27ac and H3K27me3 and thus affects the cognitive behavioral abilities of mice, we fed C57BL/6 mice with a high-methionine diet and a standard diet, then isolated the hippocampus for ChIP-seq studies of H3K27ac and H3K27me3. The sequencing data provided a new theoretical basis for the effects of high homocysteine on histone modification.2026/08/12GSE280827GSM8606262GSM8606261GSM8606257GSM8606259GSM8606258GSM860626024247280827Mus musculus[40903958]