{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE283nnn/GSE283439/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE283439"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA sequencing of neutrophils treated with microvesicles derived from glucose-deprived hepatocellular carcinoma cells.","description":"Microvesicles derived from glucose-deprived liver cancer cells can promote tumor initiation and progression through neutrophils. This phenomenon can be rescued by knocking down Ezrin. Comparative analysis revealed that microvesicles from Ezrin-knockdown (Ezrin KD) liver cancer cells exhibit downregulation of VEGFA and PD-L1, along with upregulation of angiogenesis and T-cell regulatory pathways.","dates":{"publication":"2026/04/01"},"accession":"GSE283439","cross_references":{"GSM":["GSM8662489","GSM8662493","GSM8662492","GSM8662491","GSM8662490","GSM8662494"],"GPL":["28330"],"GSE":["283439"],"taxon":["Mus musculus"]}}