{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE284nnn/GSE284257/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284257"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell RNA sequencing of hyaloid blood vessels from endothelial-specific Gpr124 knockout mice and control littermates","description":"To explore the molecular mechanisms of GPR124-mediated hyaloid blood vessel regression, single-cell RNA sequencing of hyaloid vessels from P6 endothelial-specific Gpr124 knockout mice and control littermates was performed. The sequenced cells clustered into two major populations: endothelial cells and pericytes. Differential gene expression analysis suggested that GPR124 regulates WNT/β-catenin signaling in hyaloid endothelial cells and mediates partial endothelial-mesenchymal transition (EndMT).","dates":{"publication":"2026/04/27"},"accession":"GSE284257","cross_references":{"GSM":["GSM8681098","GSM8681097","GSM8681100","GSM8681099"],"GPL":["34290"],"GSE":["284257"],"taxon":["Mus musculus"],"PMID":["[42056280]"]}}