{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284497"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptional profiling of striatum from a zQ175 KI mouse model of Huntington's disease treated with HTT-10150 siRNA targeting full-length Htt","description":"In this study we conducted a comprehensive transcriptional profiling of the striatum utilizing a zQ175 knock-in (KI) mouse model of Huntington's disease, which was treated with HTT-10150 siRNA specifically designed to target the full-length huntingtin (Htt) mRNA. Our investigation aimed to assess the impact of this intervention across different time points.","dates":{"publication":"2026/05/05"},"accession":"GSE284497","cross_references":{"GSM":["GSM8685258","GSM8685257","GSM8685259","GSM8685250","GSM8685252","GSM8685251","GSM8685254","GSM8685253","GSM8685256","GSM8685255","GSM8685368","GSM8685247","GSM8685246","GSM8685367","GSM8685249","GSM8685369","GSM8685248","GSM8685360","GSM8685362","GSM8685241","GSM8685240","GSM8685361","GSM8685243","GSM8685364","GSM8685363","GSM8685242","GSM8685366","GSM8685245","GSM8685365","GSM8685244","GSM8685357","GSM8685236","GSM8685356","GSM8685235","GSM8685359","GSM8685238","GSM8685237","GSM8685358","GSM8685239","GSM8685351","GSM8685230","GSM8685350","GSM8685353","GSM8685232","GSM8685231","GSM8685352","GSM8685234","GSM8685355","GSM8685354","GSM8685233","GSM8685346","GSM8685345","GSM8685348","GSM8685227","GSM8685347","GSM8685229","GSM8685349","GSM8685228","GSM8685340","GSM8685342","GSM8685341","GSM8685344","GSM8685343","GSM8685335","GSM8685334","GSM8685337","GSM8685336","GSM8685339","GSM8685338","GSM8685294","GSM8685293","GSM8685296","GSM8685295","GSM8685331","GSM8685298","GSM8685297","GSM8685330","GSM8685333","GSM8685299","GSM8685332","GSM8685290","GSM8685292","GSM8685291","GSM8685324","GSM8685323","GSM8685326","GSM8685325","GSM8685328","GSM8685327","GSM8685329","GSM8685283","GSM8685282","GSM8685285","GSM8685284","GSM8685320","GSM8685287","GSM8685286","GSM8685322","GSM8685289","GSM8685288","GSM8685321","GSM8685281","GSM8685280","GSM8685313","GSM8685279","GSM8685312","GSM8685315","GSM8685314","GSM8685317","GSM8685316","GSM8685319","GSM8685318","GSM8685272","GSM8685271","GSM8685274","GSM8685273","GSM8685276","GSM8685275","GSM8685311","GSM8685278","GSM8685277","GSM8685310","GSM8685270","GSM8685309","GSM8685302","GSM8685269","GSM8685268","GSM8685301","GSM8685304","GSM8685303","GSM8685306","GSM8685305","GSM8685308","GSM8685307","GSM8685261","GSM8685260","GSM8685263","GSM8685262","GSM8685265","GSM8685264","GSM8685300","GSM8685267","GSM8685266"],"GPL":["24247"],"GSE":["284497"],"taxon":["Mus musculus"],"PMID":["[41849583]"]}}