GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE284nnn/GSE284497/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284497GEOGSEfalseTranscriptional profiling of striatum from a zQ175 KI mouse model of Huntington's disease treated with HTT-10150 siRNA targeting full-length HttIn this study we conducted a comprehensive transcriptional profiling of the striatum utilizing a zQ175 knock-in (KI) mouse model of Huntington's disease, which was treated with HTT-10150 siRNA specifically designed to target the full-length huntingtin (Htt) mRNA. Our investigation aimed to assess the impact of this intervention across different time points.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 musculus[41849583]