GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE284nnn/GSE284500/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284500GEOGSEfalseTranscriptional profiling of hippocampus from a zQ175 KI mouse model of Huntington's disease treated with either HTT-10150 siRNA targeting full-length HTT or combination of HTT-634 and HTT-486 siRNAs targeting HTT1aIn this study, we conducted a comprehensive transcriptional profiling of the hippocampus utilizing a zQ175 knock-in (KI) mouse model of Huntington's disease, which was treated with either HTT-10150 siRNA specifically designed to target the full-length huntingtin (Htt) mRNA or combination of HTT-634 and HTT-486 siRNAs targeting HTT1a. Our investigation aimed to assess the impact of this intervention across different time points.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 musculus[41849583]