{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE285nnn/GSE285400/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE285400"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome of Ag-specific B cells upon stimulation with soluble or particulate Ag","description":"Primary B cells from MD4 mice have transgenic B cell receptors that recognize hen egg lysozyme (HEL). Previous studies have shown that antigens presented in different formats induce qualitatively different signaling responses in B cells. Here, we compare the transcriptomes induced by the following stimuli: LPS (10 mg/mL), particulate HEL (1pM liposomes with reduced affinity HEL-3X protein conjugated to surface at epitope density 243), soluble HEL (1mg/mL), and co-stimulation with soluble HEL and anti-CD40 (100 ng/mL).","dates":{"publication":"2026/04/23"},"accession":"GSE285400","cross_references":{"GSM":["GSM8701705","GSM8701704","GSM8701703","GSM8701702","GSM8701709","GSM8701708","GSM8701707","GSM8701706","GSM8701712","GSM8701701","GSM8701700","GSM8701711","GSM8701699","GSM8701710","GSM8701698"],"GPL":["34290"],"GSE":["285400"],"taxon":["Mus musculus"]}}