GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE285nnn/GSE285400/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE285400GEOGSEfalseTranscriptome of Ag-specific B cells upon stimulation with soluble or particulate AgPrimary B cells from MD4 mice have transgenic B cell receptors that recognize hen egg lysozyme (HEL). Previous studies have shown that antigens presented in different formats induce qualitatively different signaling responses in B cells. Here, we compare the transcriptomes induced by the following stimuli: LPS (10 mg/mL), particulate HEL (1pM liposomes with reduced affinity HEL-3X protein conjugated to surface at epitope density 243), soluble HEL (1mg/mL), and co-stimulation with soluble HEL and anti-CD40 (100 ng/mL).2026/04/23GSE285400GSM8701705GSM8701704GSM8701703GSM8701702GSM8701709GSM8701708GSM8701707GSM8701706GSM8701712GSM8701701GSM8701700GSM8701711GSM8701699GSM8701710GSM870169834290285400Mus musculus