GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE285nnn/GSE285838/primaryOK200Transcriptomics Mus musculusHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE285838GEOGSEfalseHistone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis IITo gain insight into ASF1A, ASF1B and HIRA function during erythropoiesis, RNA-seq was performed in murine erythroleukemia (MEL) cells, human umbilical cord-derived progenitor erythroid 2 (HUDEP2) cells and human CD34+ erythroid progenitor cells. Notably, depletion of ASF1A, ASF1B and HIRA with/without DMSO induction significantly reduced the expression of genes associated with erythroid differentiation. Meanwhile, depletion of ASF1A and ASF1B in HUDEP2 cells as well as depletion of ASF1B in CD34+ cells significantly reduced the expression of genes associated with erythroid differentiation.2026/05/15GSE285838GSM8709969GSM8709989GSM8709988GSM8709987GSM8709986GSM8709985GSM9023800GSM8709984GSM8709983GSM8709982GSM8709981GSM8709980GSM9023802GSM9023801GSM8709979GSM8709978GSM8709977GSM9023803GSM8709976GSM8709975GSM8709974GSM8709973GSM8709972GSM8709971GSM8709970GSM87099903428134328285838 Mus musculusHomo sapiens[42100853]