{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE287nnn/GSE287133/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE287133"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Cardiac fibroblast deletion of PTBP1 modulates the profibrotic response by alternative splicing.","description":"In this project we investigate the role of RNA binding protein PTBP1 in cardiac fibrosis through the conditional deletion of PTBP1 in mouse cardiac fibroblasts. We isolated cardiac fibroblasts from Ptbp1fl/fl mice, deleted PTBP1 with Adenoviral-Cre, and stimulated cardiac fibroblasts with TGFb to perform deep RNA sequencing studies on the cardiac fibroblast to myofibroblast transformation.","dates":{"publication":"2026/06/01"},"accession":"GSE287133","cross_references":{"GSM":["GSM8739252","GSM8739251","GSM8739243","GSM8739254","GSM8739253","GSM8739245","GSM8739244","GSM8739247","GSM8739246","GSM8739249","GSM8739248","GSM8739250"],"GPL":["24247"],"GSE":["287133"],"taxon":["Mus musculus"]}}