GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE287nnn/GSE287133/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE287133GEOGSEfalseCardiac fibroblast deletion of PTBP1 modulates the profibrotic response by alternative splicing.In this project we investigate the role of RNA binding protein PTBP1 in cardiac fibrosis through the conditional deletion of PTBP1 in mouse cardiac fibroblasts. We isolated cardiac fibroblasts from Ptbp1fl/fl mice, deleted PTBP1 with Adenoviral-Cre, and stimulated cardiac fibroblasts with TGFb to perform deep RNA sequencing studies on the cardiac fibroblast to myofibroblast transformation.2026/06/01GSE287133GSM8739252GSM8739251GSM8739243GSM8739254GSM8739253GSM8739245GSM8739244GSM8739247GSM8739246GSM8739249GSM8739248GSM873925024247287133Mus musculus