{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE287nnn/GSE287605/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":[" Genome binding/occupancy profiling by high throughput sequencing","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE287605"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Distince macrophage subpopulations in mouse wound healing","description":"Monocytes and macrophages displaying distinctive phenotypes may be pivotal in coordinating the transition between different stages of wound healing. RNAseq results showed that day 1 macrophages segregated from day 4 and 7 macrophages, and that on days 4 and 7 macrophages segregated primarily based on F4/80-low versus F4/80-high phenotype. TNF and IL-4 pathways converge in F4/80-low macrophages at 4 days after skin wound healing, these F4/80-low macrophages express inflammatory, MHC class II and a subset of IL-4 target genes. Footprinting analysis on ATAC-seq data revealed enrichement of both NFKB1 and STAT6 in F4/80-low macrophages at 4 dp, whereas the overall differences in transcription factor binding between F4/80-high and F4/80-low macrophages diminished by 7 dpi.","dates":{"publication":"2026/09/02"},"accession":"GSE287605","cross_references":{"GSM":["GSM8748814","GSM8748813","GSM8748812","GSM8748811","GSM8748833","GSM8748832","GSM8748810","GSM8748831","GSM8748830","GSM8748819","GSM8748818","GSM8748817","GSM8748816","GSM8748815","GSM8748825","GSM8748824","GSM8748823","GSM8748822","GSM8748821","GSM8748820","GSM8748809","GSM8748808","GSM8748829","GSM8748807","GSM8748806","GSM8748828","GSM8748805","GSM8748827","GSM8748804","GSM8748826"],"GPL":["34290"],"GSE":["287605"],"taxon":["Mus musculus"]}}