{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE288nnn/GSE288676/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE288676"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell Sequencing Analysis-driven Nanomedicine Design for Mimicking Endogenous Immune Repair in Myocardial Infarction","description":"We present a data - driven biomimetic strategy. Single - cell RNA sequencing was used to analyze immune cell changes post - MI, uncovering macrophage subtypes' distinct roles at different recovery stages. Based on this, we developed immune cell - mimicking nanoparticles and a sequential delivery strategy to imitate the temporal distribution of M2a, M2b, and M2c macrophage subtypes in the MI repair process.","dates":{"publication":"2026/03/30"},"accession":"GSE288676","cross_references":{"GSM":["GSM8772922","GSM8772911","GSM8772923","GSM8772912","GSM8772920","GSM8772910","GSM8772921","GSM8772908","GSM8772919","GSM8772909","GSM8772917","GSM8772907","GSM8772918","GSM8772915","GSM8772916","GSM8772913","GSM8772924","GSM8772914"],"GPL":["28330"],"GSE":["288676"],"taxon":["Mus musculus"]}}