GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE288nnn/GSE288676/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE288676GEOGSEfalseSingle-cell Sequencing Analysis-driven Nanomedicine Design for Mimicking Endogenous Immune Repair in Myocardial InfarctionWe present a data - driven biomimetic strategy. Single - cell RNA sequencing was used to analyze immune cell changes post - MI, uncovering macrophage subtypes' distinct roles at different recovery stages. Based on this, we developed immune cell - mimicking nanoparticles and a sequential delivery strategy to imitate the temporal distribution of M2a, M2b, and M2c macrophage subtypes in the MI repair process.2026/03/30GSE288676GSM8772922GSM8772911GSM8772923GSM8772912GSM8772920GSM8772910GSM8772921GSM8772908GSM8772919GSM8772909GSM8772917GSM8772907GSM8772918GSM8772915GSM8772916GSM8772913GSM8772924GSM877291428330288676Mus musculus