GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE289nnn/GSE289731/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE289731GEOGSEfalseEffect of overexpression of Lipoprotein lipase (LPL) on MS-1 endothelial cellsImmune regulation of endothelial cell is esstential for efficient anti-tumor T cell immunity.We here report LPL lipoprotein lipase as a key regulator of endothelial immune response. The overexpression of LPL results in enhanced antigen presentation on endothelial cell, which in turns enhance T cell homing.Moreover, LPL also enhance the sensitivity of EC to IFN-g exposure, with elevated percentage of apoptotic cells. Taken together, our data provide a molecular framework of the effect of LPL on endothelial cells.2026/05/20GSE289731GSM8797659GSM8797656GSM8797655GSM8797658GSM8797657GSM8797654GSM879766021626289731Mus musculus