GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE291nnn/GSE291017/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE291017GEOGSEfalseAccumulation of mutant Z α1-Antitrypsin impairs intestinal function in miceWe found that accumulation of mutant Z α1-Antitrypsin in intestinal cells, and in particular in Paneth cells, induces activation of proteotoxic pathways leading to impaired intestinla homeostasis in PiZ mice.2026/06/29GSE291017GSM8827621GSM8827620GSM8827627GSM8827626GSM8827625GSM8827624GSM8827623GSM882762224247291017Mus musculus