{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE291nnn/GSE291782/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE291782"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-Cell Transcriptomics Highlights Macrophage-Driven Regulation of EndMT and Repair in Injured Muscle","description":"This study investigates the interactions between innate immune cells and vascular-associated cells within the regenerating muscle niche. Specifically, the transcriptomes of Cdh5-CreERT2:R26R-tdTomato mice were analysed following the partial ablation of infiltrating macrophages (MPs) to understand their influence on endothelial cell (EC) behaviour after injury. This work provides a comprehensive transcriptomic signature of the regenerative muscle niche and highlights key molecular interactions between MPs and ECs.","dates":{"publication":"2026/04/21"},"accession":"GSE291782","cross_references":{"GSM":["GSM8842372","GSM8842371","GSM8842374","GSM8842373","GSM8842376","GSM8842375"],"GPL":["24247"],"GSE":["291782"],"taxon":["Mus musculus"]}}