{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE292nnn/GSE292556/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE292556"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of hepatic FPN ablation on the liver transcriptome in mice","description":"Iron overload has emerged as a key risk factor for MASLD and metabolic disorders. We explored the effects of hepatocyte-specific knockout of ferroportin (FPN), the only known iron exporter, on the pathogenesis of MASLD and the associated metabolic dysfunction. To investigate the molecular basis, we carried out RNA-sequencing analysis using liver samples from littermate control and hepatocyte-specific Fpn KO mice.","dates":{"publication":"2026/04/14"},"accession":"GSE292556","cross_references":{"GSM":["GSM8861399","GSM8861398","GSM8861401","GSM8861400","GSM8861403","GSM8861402"],"GPL":["24247"],"GSE":["292556"],"taxon":["Mus musculus"]}}