{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293613/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293613"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Tbl1xr1 KI heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293613","cross_references":{"GSM":["GSM8886882","GSM8886881","GSM8886880","GSM8886886","GSM8886842","GSM8886841","GSM8886885","GSM8886884","GSM8886840","GSM8886883","GSM8886846","GSM8886845","GSM8886844","GSM8886843","GSM8886849","GSM8886848","GSM8886847","GSM8886829","GSM8886871","GSM8886870","GSM8886875","GSM8886831","GSM8886830","GSM8886874","GSM8886873","GSM8886872","GSM8886835","GSM8886879","GSM8886878","GSM8886834","GSM8886833","GSM8886877","GSM8886832","GSM8886876","GSM8886839","GSM8886838","GSM8886837","GSM8886836","GSM8886860","GSM8886864","GSM8886863","GSM8886862","GSM8886861","GSM8886868","GSM8886867","GSM8886866","GSM8886865","GSM8886869","GSM8886853","GSM8886852","GSM8886851","GSM8886850","GSM8886857","GSM8886856","GSM8886855","GSM8886854","GSM8886859","GSM8886858"],"GPL":["24247"],"GSE":["293613"],"taxon":["Mus musculus"]}}