GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293613/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293613GEOGSEfalseTranscriptome analysis in the prefrontal cortex of Tbl1xr1 KI heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups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 musculus