GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293614/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293614GEOGSEfalseTranscriptome analysis in the prefrontal cortex of Dyrk1a+/I48X heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups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 musculus