{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293620/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293620"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Scn2a heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293620","cross_references":{"GSM":["GSM8887090","GSM8887095","GSM8887051","GSM8887052","GSM8887096","GSM8887053","GSM8887097","GSM8887098","GSM8887054","GSM8887091","GSM8887092","GSM8887093","GSM8887050","GSM8887094","GSM8887059","GSM8887055","GSM8887099","GSM8887056","GSM8887057","GSM8887058","GSM8887084","GSM8887085","GSM8887086","GSM8887087","GSM8887080","GSM8887081","GSM8887082","GSM8887083","GSM8887088","GSM8887089","GSM8887073","GSM8887074","GSM8887075","GSM8887076","GSM8887070","GSM8887071","GSM8887072","GSM8887077","GSM8887078","GSM8887079","GSM8887062","GSM8887063","GSM8887064","GSM8887065","GSM8887060","GSM8887061","GSM8887103","GSM8887104","GSM8887105","GSM8887066","GSM8887067","GSM8887100","GSM8887101","GSM8887068","GSM8887069","GSM8887102"],"GPL":["24247"],"GSE":["293620"],"taxon":["Mus musculus"]}}