GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293620/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293620GEOGSEfalseTranscriptome analysis in the prefrontal cortex of Scn2a heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.2026/07/28GSE293620GSM8887090GSM8887095GSM8887051GSM8887052GSM8887096GSM8887053GSM8887097GSM8887098GSM8887054GSM8887091GSM8887092GSM8887093GSM8887050GSM8887094GSM8887059GSM8887055GSM8887099GSM8887056GSM8887057GSM8887058GSM8887084GSM8887085GSM8887086GSM8887087GSM8887080GSM8887081GSM8887082GSM8887083GSM8887088GSM8887089GSM8887073GSM8887074GSM8887075GSM8887076GSM8887070GSM8887071GSM8887072GSM8887077GSM8887078GSM8887079GSM8887062GSM8887063GSM8887064GSM8887065GSM8887060GSM8887061GSM8887103GSM8887104GSM8887105GSM8887066GSM8887067GSM8887100GSM8887101GSM8887068GSM8887069GSM888710224247293620Mus musculus