{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293621/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293621"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Ash1l heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293621","cross_references":{"GSM":["GSM8887130","GSM8887131","GSM8887136","GSM8887137","GSM8887138","GSM8887139","GSM8887132","GSM8887133","GSM8887134","GSM8887135","GSM8887161","GSM8887162","GSM8887163","GSM8887120","GSM8887164","GSM8887160","GSM8887125","GSM8887126","GSM8887127","GSM8887128","GSM8887121","GSM8887122","GSM8887123","GSM8887124","GSM8887129","GSM8887150","GSM8887151","GSM8887152","GSM8887153","GSM8887114","GSM8887158","GSM8887159","GSM8887115","GSM8887116","GSM8887117","GSM8887154","GSM8887110","GSM8887111","GSM8887155","GSM8887112","GSM8887156","GSM8887157","GSM8887113","GSM8887118","GSM8887119","GSM8887140","GSM8887141","GSM8887142","GSM8887147","GSM8887148","GSM8887149","GSM8887106","GSM8887143","GSM8887144","GSM8887145","GSM8887146","GSM8887107","GSM8887108","GSM8887109"],"GPL":["24247"],"GSE":["293621"],"taxon":["Mus musculus"]}}