GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293621/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293621GEOGSEfalseTranscriptome analysis in the prefrontal cortex of Ash1l heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.2026/07/28GSE293621GSM8887130GSM8887131GSM8887136GSM8887137GSM8887138GSM8887139GSM8887132GSM8887133GSM8887134GSM8887135GSM8887161GSM8887162GSM8887163GSM8887120GSM8887164GSM8887160GSM8887125GSM8887126GSM8887127GSM8887128GSM8887121GSM8887122GSM8887123GSM8887124GSM8887129GSM8887150GSM8887151GSM8887152GSM8887153GSM8887114GSM8887158GSM8887159GSM8887115GSM8887116GSM8887117GSM8887154GSM8887110GSM8887111GSM8887155GSM8887112GSM8887156GSM8887157GSM8887113GSM8887118GSM8887119GSM8887140GSM8887141GSM8887142GSM8887147GSM8887148GSM8887149GSM8887106GSM8887143GSM8887144GSM8887145GSM8887146GSM8887107GSM8887108GSM888710924247293621Mus musculus