{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293627/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293627"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Shank3 delta C heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293627","cross_references":{"GSM":["GSM8887293","GSM8887294","GSM8887295","GSM8887296","GSM8887290","GSM8887291","GSM8887292","GSM8887297","GSM8887298","GSM8887299","GSM8887282","GSM8887283","GSM8887284","GSM8887285","GSM8887280","GSM8887281","GSM8887323","GSM8887324","GSM8887286","GSM8887287","GSM8887320","GSM8887321","GSM8887288","GSM8887322","GSM8887289","GSM8887271","GSM8887272","GSM8887273","GSM8887274","GSM8887270","GSM8887279","GSM8887312","GSM8887313","GSM8887314","GSM8887315","GSM8887275","GSM8887276","GSM8887310","GSM8887277","GSM8887278","GSM8887311","GSM8887316","GSM8887317","GSM8887318","GSM8887319","GSM8887301","GSM8887268","GSM8887302","GSM8887269","GSM8887303","GSM8887304","GSM8887300","GSM8887309","GSM8887305","GSM8887306","GSM8887307","GSM8887308"],"GPL":["24247"],"GSE":["293627"],"taxon":["Mus musculus"]}}