{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293635/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293635"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Kmt5b heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293635","cross_references":{"GSM":["GSM8887491","GSM8887492","GSM8887493","GSM8887494","GSM8887490","GSM8887532","GSM8887499","GSM8887533","GSM8887534","GSM8887535","GSM8887495","GSM8887496","GSM8887497","GSM8887530","GSM8887531","GSM8887498","GSM8887536","GSM8887537","GSM8887538","GSM8887539","GSM8887488","GSM8887521","GSM8887522","GSM8887489","GSM8887523","GSM8887524","GSM8887484","GSM8887485","GSM8887486","GSM8887520","GSM8887487","GSM8887529","GSM8887525","GSM8887526","GSM8887527","GSM8887528","GSM8887510","GSM8887511","GSM8887512","GSM8887513","GSM8887518","GSM8887519","GSM8887514","GSM8887515","GSM8887516","GSM8887517","GSM8887500","GSM8887501","GSM8887502","GSM8887540","GSM8887541","GSM8887507","GSM8887508","GSM8887509","GSM8887503","GSM8887504","GSM8887505","GSM8887506"],"GPL":["24247"],"GSE":["293635"],"taxon":["Mus musculus"]}}