GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293700/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293700GEOGSEfalseTranscriptome analysis in the prefrontal cortex of PTEN KI heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.2026/07/28GSE293700GSM8888742GSM8888743GSM8888700GSM8888744GSM8888701GSM8888745GSM8888740GSM8888741GSM8888706GSM8888707GSM8888708GSM8888709GSM8888746GSM8888702GSM8888703GSM8888747GSM8888704GSM8888748GSM8888749GSM8888705GSM8888731GSM8888732GSM8888733GSM8888734GSM8888730GSM8888739GSM8888735GSM8888736GSM8888737GSM8888738GSM8888720GSM8888721GSM8888722GSM8888723GSM8888728GSM8888729GSM8888724GSM8888725GSM8888726GSM8888727GSM8888753GSM8888710GSM8888754GSM8888755GSM8888711GSM8888712GSM8888756GSM8888750GSM8888751GSM8888752GSM8888717GSM8888718GSM8888719GSM8888757GSM8888713GSM8888714GSM8888758GSM8888759GSM8888715GSM888871624247293700Mus musculus